Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor–induced Nur77 expression and apoptosis

The molecular basis of thymocyte negative selection, a crucial mechanism in establishing central tolerance, is not yet resolved. Histone deacetylases (HDACs) have emerged as key transcriptional regulators in several major developmental programs. Recently, we showed that the class IIa member, HDAC7,...

Descripción completa

Detalles Bibliográficos
Autores principales: Dequiedt, Franck, Van Lint, Johan, Lecomte, Emily, Van Duppen, Viktor, Seufferlein, Thomas, Vandenheede, Jackie R., Wattiez, Ruddy, Kettmann, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212830/
https://www.ncbi.nlm.nih.gov/pubmed/15738054
http://dx.doi.org/10.1084/jem.20042034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212830/
https://www.ncbi.nlm.nih.gov/pubmed/15738054
http://dx.doi.org/10.1084/jem.20042034

Ejemplares similares