Cargando…
T cells that cannot respond to TGF-β escape control by CD4(+)CD25(+) regulatory T cells
CD4(+)CD25(+) regulatory T (T reg) cells play a pivotal role in control of the immune response. Transforming growth factor-β (TGF-β) has been shown to be required for T reg cell activity; however, precisely how it is involved in the mechanism of suppression is poorly understood. Using the T cell tra...
Autores principales: | Fahlén, Linda, Read, Simon, Gorelik, Leonid, Hurst, Stephen D., Coffman, Robert L., Flavell, Richard A., Powrie, Fiona |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212836/ https://www.ncbi.nlm.nih.gov/pubmed/15753207 http://dx.doi.org/10.1084/jem.20040685 |
Ejemplares similares
-
Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25(+)Cd4(+) Regulatory Cells That Control Intestinal Inflammation
por: Read, Simon, et al.
Publicado: (2000) -
Conversion of Peripheral CD4(+)CD25(−) Naive T Cells to CD4(+)CD25(+) Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3
por: Chen, WanJun, et al.
Publicado: (2003) -
CD4(+)CD25(+) T(R) Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms
por: Maloy, Kevin J., et al.
Publicado: (2003) -
TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells
por: Marie, Julien C., et al.
Publicado: (2005) -
CD4(+)CD25(+) T regulatory cells in renal transplantation
por: Cheung, Jason, et al.
Publicado: (2022)