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Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is a disease that can involve one or multiple organ systems characterized by an accumulation of CD1a(+) Langerhans-like cells as well as several other myeloid cell types. The precise origin and role of one of these populations, the multinucleated giant cell (MGC),...
Autores principales: | da Costa, Cristiana E.T., Annels, Nicola E., Faaij, Claudia M.J.M., Forsyth, Ramses G., Hogendoorn, Pancras C.W., Egeler, R. Maarten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212837/ https://www.ncbi.nlm.nih.gov/pubmed/15753204 http://dx.doi.org/10.1084/jem.20041785 |
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