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Repression of SPI2 transcription by nitric oxide-producing, IFNγ-activated macrophages promotes maturation of Salmonella phagosomes

By remodeling the phagosomal membrane, the type III secretion system encoded within the Salmonella pathogenicity island-2 (SPI2) helps Salmonella thrive within professional phagocytes. We report here that nitric oxide (NO) generated by IFNγ-activated macrophages abrogates the intracellular survival...

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Detalles Bibliográficos
Autores principales: McCollister, Bruce D., Bourret, Travis J., Gill, Ronald, Jones-Carson, Jessica, Vázquez-Torres, Andrés
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212872/
https://www.ncbi.nlm.nih.gov/pubmed/16129704
http://dx.doi.org/10.1084/jem.20050246

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