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Repression of SPI2 transcription by nitric oxide-producing, IFNγ-activated macrophages promotes maturation of Salmonella phagosomes
By remodeling the phagosomal membrane, the type III secretion system encoded within the Salmonella pathogenicity island-2 (SPI2) helps Salmonella thrive within professional phagocytes. We report here that nitric oxide (NO) generated by IFNγ-activated macrophages abrogates the intracellular survival...
Autores principales: | McCollister, Bruce D., Bourret, Travis J., Gill, Ronald, Jones-Carson, Jessica, Vázquez-Torres, Andrés |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212872/ https://www.ncbi.nlm.nih.gov/pubmed/16129704 http://dx.doi.org/10.1084/jem.20050246 |
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