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MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells

During pathologic vessel remodeling, vascular smooth muscle cells (VSMCs) embedded within the collagen-rich matrix of the artery wall mobilize uncharacterized proteolytic systems to infiltrate the subendothelial space and generate neointimal lesions. Although the VSMC-derived serine proteinases, pla...

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Detalles Bibliográficos
Autores principales: Filippov, Sergey, Koenig, Gerald C., Chun, Tae-Hwa, Hotary, Kevin B., Ota, Ichiro, Bugge, Thomas H., Roberts, Joseph D., Fay, William P., Birkedal-Hansen, Henning, Holmbeck, Kenn, Sabeh, Farideh, Allen, Edward D., Weiss, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212885/
https://www.ncbi.nlm.nih.gov/pubmed/16147977
http://dx.doi.org/10.1084/jem.20050607

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