BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation

Leukotriene B(4) is a lipid mediator that recently has been shown to have potent chemotactic activity for effector T lymphocytes mediated through its receptor, BLT1. Here, we developed a novel murine model of acute lung rejection to demonstrate that BLT1 controls effector CD8(+) T cell trafficking i...

Descripción completa

Detalles Bibliográficos
Autores principales: Medoff, Benjamin D., Seung, Edward, Wain, John C., Means, Terry K., Campanella, Gabriele S.V., Islam, Sabina A., Thomas, Seddon Y., Ginns, Leo C., Grabie, Nir, Lichtman, Andrew H., Tager, Andrew M., Luster, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212891/
https://www.ncbi.nlm.nih.gov/pubmed/15998790
http://dx.doi.org/10.1084/jem.20042481

Ejemplares similares

Ejemplares similares