Cargando…

Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn

SAP is an adaptor protein that is expressed in NK and T cells. It is mutated in humans who have X-linked lymphoproliferative (XLP) disease. By interacting with SLAM family receptors, SAP enables tyrosine phosphorylation signaling of these receptors by its ability to recruit the Src-related kinase, F...

Descripción completa

Detalles Bibliográficos
Autores principales: Bloch-Queyrat, Coralie, Fondanèche, Marie-Claude, Chen, Riyan, Yin, Luo, Relouzat, Francis, Veillette, André, Fischer, Alain, Latour, Sylvain
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212903/
https://www.ncbi.nlm.nih.gov/pubmed/15998796
http://dx.doi.org/10.1084/jem.20050449