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Impaired early B cell tolerance in patients with rheumatoid arthritis
Autoantibody production is a characteristic of most autoimmune diseases including rheumatoid arthritis (RA). The role of these autoantibodies in the pathogenesis of RA remains elusive, but they appear in the serum many years before the onset of clinical disease suggesting an early break in B cell to...
Autores principales: | Samuels, Jonathan, Ng, Yen-Shing, Coupillaud, Claire, Paget, Daniel, Meffre, Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212916/ https://www.ncbi.nlm.nih.gov/pubmed/15897279 http://dx.doi.org/10.1084/jem.20042321 |
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