A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses

A mouse cytomegalovirus (MCMV) gene conferring interferon (IFN) resistance was identified. This gene, M27, encodes a 79-kD protein that selectively binds and down-regulates for signal transducer and activator of transcription (STAT)-2, but it has no effect on STAT1 activation and signaling. The abse...

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Detalles Bibliográficos
Autores principales: Zimmermann, Albert, Trilling, Mirko, Wagner, Markus, Wilborn, Manuel, Bubic, Ivan, Jonjic, Stipan, Koszinowski, Ulrich, Hengel, Hartmut
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212917/
https://www.ncbi.nlm.nih.gov/pubmed/15883169
http://dx.doi.org/10.1084/jem.20041401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212917/
https://www.ncbi.nlm.nih.gov/pubmed/15883169
http://dx.doi.org/10.1084/jem.20041401

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