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AID from bony fish catalyzes class switch recombination

Class switch recombination was the last of the lymphocyte-specific DNA modification reactions to appear in the evolution of the adaptive immune system. It is absent in cartilaginous and bony fish, and it is common to all tetrapods. Class switching is initiated by activation-induced cytidine deaminas...

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Detalles Bibliográficos
Autores principales:	Barreto, Vasco M., Pan-Hammarstrom, Qiang, Zhao, Yaofeng, Hammarstrom, Lennart, Misulovin, Ziva, Nussenzweig, Michel C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212934/ https://www.ncbi.nlm.nih.gov/pubmed/16157688 http://dx.doi.org/10.1084/jem.20051378

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