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Continuous control of autoimmune disease by antigen-dependent polyclonal CD4(+)CD25(+) regulatory T cells in the regional lymph node
This study investigated the unresolved issue of antigen-dependency and antigen-specificity of autoimmune disease suppression by CD4(+)CD25(+) T cells (T regs). Based on autoimmune ovarian disease (AOD) in day 3 thymectomized (d3tx) mice and polyclonal T regs expressing the Thy1.1 marker, we determin...
Autores principales: | Samy, Eileen T., Parker, Lucy A., Sharp, Colin P., Tung, Kenneth S.K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212949/ https://www.ncbi.nlm.nih.gov/pubmed/16172257 http://dx.doi.org/10.1084/jem.20041033 |
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