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Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder
Caspase-8 is best known for its cell death function via death receptors. Recent evidence indicates that caspase-8 also has nonapoptotic functions. Caspase-8 deficiency is associated with pathologies that are unexpected for a proapoptotic molecule, such as abrogation of activation-induced lymphocyte...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212954/ https://www.ncbi.nlm.nih.gov/pubmed/16157684 http://dx.doi.org/10.1084/jem.20050683 |