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Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding
Secretory leucoprotease inhibitor (SLPI) is a nonglycosylated protein produced by epithelial cells. In addition to its antiprotease activity, SLPI has been shown to exhibit antiinflammatory properties, including down-regulation of tumor necrosis factor α expression by lipopolysaccharide (LPS) in mac...
Autores principales: | Taggart, Clifford C., Cryan, Sally-Ann, Weldon, Sinead, Gibbons, Aileen, Greene, Catherine M., Kelly, Emer, Low, Teck Boon, O'Neill, Shane J., McElvaney, Noel G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212970/ https://www.ncbi.nlm.nih.gov/pubmed/16352738 http://dx.doi.org/10.1084/jem.20050768 |
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