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Where CD4(+)CD25(+) T reg cells impinge on autoimmune diabetes

Foxp3 is required for the generation and activity of CD4(+)CD25(+) regulatory T (T reg) cells, which are important controllers of autoimmunity, including type-1 diabetes. To determine where T reg cells affect the diabetogenic cascade, we crossed the Foxp3 scurfy mutation, which eliminates T reg cell...

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Detalles Bibliográficos
Autores principales:	Chen, Zhibin, Herman, Ann E., Matos, Michael, Mathis, Diane, Benoist, Christophe
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212985/ https://www.ncbi.nlm.nih.gov/pubmed/16301745 http://dx.doi.org/10.1084/jem.20051409

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