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Avidity for antigen shapes clonal dominance in CD8(+) T cell populations specific for persistent DNA viruses

The forces that govern clonal selection during the genesis and maintenance of specific T cell responses are complex, but amenable to decryption by interrogation of constituent clonotypes within the antigen-experienced T cell pools. Here, we used point-mutated peptide–major histocompatibility complex...

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Detalles Bibliográficos
Autores principales:	Price, David A., Brenchley, Jason M., Ruff, Laura E., Betts, Michael R., Hill, Brenna J., Roederer, Mario, Koup, Richard A., Migueles, Steven A., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Connors, Mark, Douek, Daniel C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212993/ https://www.ncbi.nlm.nih.gov/pubmed/16287711 http://dx.doi.org/10.1084/jem.20051357

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