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Defective thrombus formation in mice lacking coagulation factor XII

Blood coagulation is thought to be initiated by plasma protease factor VIIa in complex with the membrane protein tissue factor. In contrast, coagulation factor XII (FXII)–mediated fibrin formation is not believed to play an important role for coagulation in vivo. We used FXII-deficient mice to study...

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Detalles Bibliográficos
Autores principales:	Renné, Thomas, Pozgajová, Miroslava, Grüner, Sabine, Schuh, Kai, Pauer, Hans-Ulrich, Burfeind, Peter, Gailani, David, Nieswandt, Bernhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213000/ https://www.ncbi.nlm.nih.gov/pubmed/16009717 http://dx.doi.org/10.1084/jem.20050664

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