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The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells

Neuromedin U (NMU) is a neuropeptide that is expressed in the gastrointestinal tract and central nervous system. NMU interacts with two G protein–coupled receptors, NMU-R1 and NMU-R2. Whereas NMU-R2 localizes predominantly to nerve cells, NMU-R1 is expressed in peripheral tissues including lymphocyt...

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Detalles Bibliográficos
Autores principales: Moriyama, Maiko, Sato, Takahiro, Inoue, Hiromasa, Fukuyama, Satoru, Teranishi, Hitoshi, Kangawa, Kenji, Kano, Tatsuhiko, Yoshimura, Akihiko, Kojima, Masayasu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213011/
https://www.ncbi.nlm.nih.gov/pubmed/16009716
http://dx.doi.org/10.1084/jem.20050248