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CD8(+) immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells

Antigen immunodominance is an unexplained feature of CD8(+) T cell responses to herpesviruses, which are agents whose lytic replication involves the sequential expression of immediate early (IE), early (E), and late (L) proteins. Here, we analyze the primary CD8 response to Epstein-Barr virus (EBV)...

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Detalles Bibliográficos
Autores principales:	Pudney, Victoria A., Leese, Alison M., Rickinson, Alan B., Hislop, Andrew D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213038/ https://www.ncbi.nlm.nih.gov/pubmed/15684323 http://dx.doi.org/10.1084/jem.20041542

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