Selecting B cells and plasma cells to memory

Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selecte...

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Detalles Bibliográficos
Autores principales: Dörner, Thomas, Radbruch, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213048/
https://www.ncbi.nlm.nih.gov/pubmed/15728231
http://dx.doi.org/10.1084/jem.20050218
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author Dörner, Thomas
Radbruch, Andreas
author_facet Dörner, Thomas
Radbruch, Andreas
author_sort Dörner, Thomas
collection PubMed
description Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic.
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spelling pubmed-22130482008-03-11 Selecting B cells and plasma cells to memory Dörner, Thomas Radbruch, Andreas J Exp Med Commentary Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic. The Rockefeller University Press 2005-02-21 /pmc/articles/PMC2213048/ /pubmed/15728231 http://dx.doi.org/10.1084/jem.20050218 Text en Copyright © 2005, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Dörner, Thomas
Radbruch, Andreas
Selecting B cells and plasma cells to memory
title Selecting B cells and plasma cells to memory
title_full Selecting B cells and plasma cells to memory
title_fullStr Selecting B cells and plasma cells to memory
title_full_unstemmed Selecting B cells and plasma cells to memory
title_short Selecting B cells and plasma cells to memory
title_sort selecting b cells and plasma cells to memory
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213048/
https://www.ncbi.nlm.nih.gov/pubmed/15728231
http://dx.doi.org/10.1084/jem.20050218
work_keys_str_mv AT dornerthomas selectingbcellsandplasmacellstomemory
AT radbruchandreas selectingbcellsandplasmacellstomemory

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