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An essential role for c-FLIP in the efficient development of mature T lymphocytes

Apoptosis-related genes play important roles in thymocyte maturation. We show that cellular FLICE-like inhibitory protein (c-FLIP), a procaspase-8–like apoptotic regulator, plays an essential role in the efficient development of mature T lymphocytes. Mice conditionally lacking c-FLIP in T lymphocyte...

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Detalles Bibliográficos
Autores principales: Zhang, Nu, He, You-Wen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213074/
https://www.ncbi.nlm.nih.gov/pubmed/16043517
http://dx.doi.org/10.1084/jem.20050117