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Organic cation transporter 3 modulates murine basophil functions by controlling intracellular histamine levels

In this study, we identify the bidirectional organic cation transporter 3 (OCT3/Slc22a3) as the molecule responsible for histamine uptake by murine basophils. We demonstrate that OCT3 participates in the control of basophil functions because exogenous histamine can inhibit its own synthesis—and that...

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Detalles Bibliográficos
Autores principales:	Schneider, Elke, Machavoine, François, Pléau, Jean-Marie, Bertron, Anne-France, Thurmond, Robin L., Ohtsu, Hiroshi, Watanabe, Takehiko, Schinkel, Alfred H., Dy, Michel
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213077/ https://www.ncbi.nlm.nih.gov/pubmed/16061728 http://dx.doi.org/10.1084/jem.20050195

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