Cargando…

Signaling for NKT cell development: the SAP–FynT connection

New studies demonstrate a critical role for the adaptor protein SAP (SLAM-associated protein) during NKT cell development. By connecting homotypic SLAM family receptor interactions with the FynT Src kinase, SAP may integrate a set of long-standing yet seemingly disparate observations characterizing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borowski, Christine, Bendelac, Albert
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213098/ https://www.ncbi.nlm.nih.gov/pubmed/15781574 http://dx.doi.org/10.1084/jem.20050339

Ejemplares similares

SLAM-SAP-Fyn: Old Players with New Roles in iNKT Cell Development and Function
por: Bahal, Devika, et al.
Publicado: (2019)

Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes
por: Lee, Chingli, et al.
Publicado: (2017)

Isoform‐specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias
por: Low, Clara Y. B., et al.
Publicado: (2021)

NKT cells depend on SAP
por: Van Epps, Heather L.
Publicado: (2005)

Involvement of p59fynT in interleukin-5 receptor signaling [published erratum appears in J Exp Med 1995 Oct 1;182(4):1179]
Publicado: (1995)

Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity
por: Chen, Shasha, et al.
Publicado: (2017)

Characterization of the early stages of thymic NKT cell development
por: Benlagha, Kamel, et al.
Publicado: (2005)

Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn
por: Bloch-Queyrat, Coralie, et al.
Publicado: (2005)

Selection and Adaptation of Cells Expressing Major Histocompatibility Complex Class I–specific Receptors of the Natural Killer Complex
por: Bendelac, Albert
Publicado: (1997)

Functionally distinct NKT cell subsets and subtypes
por: Seino, Ken-ichiro, et al.
Publicado: (2005)

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
por: Pasquier, Benoit, et al.
Publicado: (2005)

Adjuvants of Immunity : Harnessing Innate Immunity to Promote Adaptive Immunity
por: Bendelac, Albert, et al.
Publicado: (2002)

Elevated and sustained Egr1 and Egr2 expression controls NKT lineage differentiation in response to TCR signaling
por: Seiler, Michael P., et al.
Publicado: (2012)

Invariant NKT Cells as Initiators, Licensors, and Facilitators of the Adaptive Immune Response
por: Stein-Streilein, Joan
Publicado: (2003)

NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma
por: McKnight, Christopher G., et al.
Publicado: (2017)

Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation
por: Scanlon, Seth T., et al.
Publicado: (2011)

Dendritic Cell Maturation Overrules H-2d–Mediated Natural Killer T (Nkt) Cell Inhibition: Critical Role for B7 in Cd1d-Dependent Nkt Cell Interferon γ Production
por: Ikarashi, Yoshinori, et al.
Publicado: (2001)

Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
por: Wei, Datsen G., et al.
Publicado: (2005)

Fyn regeneration
por: Short, Ben
Publicado: (2012)

The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells
por: Schrantz, Nicolas, et al.
Publicado: (2007)

SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
por: Veillette, André
Publicado: (2004)

Immune cells and preterm labour: do invariant NKT cells hold the key?
por: Rinaldi, S.F., et al.
Publicado: (2015)

Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy
por: TANIGUCHI, Masaru, et al.
Publicado: (2015)

Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines
por: Khan, Masood Alam, et al.
Publicado: (2021)

The GSK-3β/Fyn/Nrf2 pathway in fibroblasts and wounds of type 2 diabetes: On the road to an evidence-based therapy of non-healing wounds
por: Bitar, Milad S.
Publicado: (2012)

The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells
por: Yasuoka, Toshiaki, et al.
Publicado: (2016)

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance
por: Meriane, Mayya, et al.
Publicado: (2004)

Fyn amplifies NLRP3 inflammasome signaling in Parkinson's disease
por: Panicker, Nikhil, et al.
Publicado: (2019)

Fyn Signaling in Ischemia-Reperfusion Injury: Potential and Therapeutic Implications
por: Du, Fang, et al.
Publicado: (2022)

iNKT cell development is orchestrated by different branches of TGF-β signaling
por: Doisne, Jean-Marc, et al.
Publicado: (2009)

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

The Role of Autophagy in iNKT Cell Development
por: Yang, Guan, et al.
Publicado: (2018)

Recent advances in iNKT cell development
por: Hogquist, Kristin, et al.
Publicado: (2020)

The Src Family Tyrosine Kinase Fyn Regulates Natural Killer T Cell Development
por: Gadue, Paul, et al.
Publicado: (1999)

NKT Cells in Sepsis
por: Leung, Briana, et al.
Publicado: (2010)

Itk and Fyn Make Independent Contributions to T Cell Activation
por: Liao, X. Charlene, et al.
Publicado: (1997)

Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function
por: Liu, Qian, et al.
Publicado: (2022)

Connecting G protein signaling to chemoattractant-mediated cell polarity and cytoskeletal reorganization
por: Liu, Youtao, et al.
Publicado: (2016)

Manage your SAP projects with SAP Activate: implementing SAP S/4HANA
por: Singh, Vinay
Publicado: (2017)

Metastases: the glycan connection
por: Couldrey, Christine, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_j34runqpeb0rcdt0d6idu31d09