Cargando…
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
Rhinoviruses are the major trigger of acute asthma exacerbations and asthmatic subjects are more susceptible to these infections. To investigate the underlying mechanisms of this increased susceptibility, we examined virus replication and innate responses to rhinovirus (RV)-16 infection of primary b...
Autores principales: | Wark, Peter A.B., Johnston, Sebastian L., Bucchieri, Fabio, Powell, Robert, Puddicombe, Sarah, Laza-Stanca, Vasile, Holgate, Stephen T., Davies, Donna E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213100/ https://www.ncbi.nlm.nih.gov/pubmed/15781584 http://dx.doi.org/10.1084/jem.20041901 |
Ejemplares similares
-
Cigarette Smoke Causes Caspase-Independent Apoptosis of Bronchial Epithelial Cells from Asthmatic Donors
por: Bucchieri, Fabio, et al.
Publicado: (2015) -
Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response
por: Bedke, Nicole, et al.
Publicado: (2012) -
IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations
por: Wark, Peter A.B., et al.
Publicado: (2007) -
Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
por: Gielen, Vera, et al.
Publicado: (2015) -
Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection
por: Veerati, Punnam Chander, et al.
Publicado: (2023)