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Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

Rhinoviruses are the major trigger of acute asthma exacerbations and asthmatic subjects are more susceptible to these infections. To investigate the underlying mechanisms of this increased susceptibility, we examined virus replication and innate responses to rhinovirus (RV)-16 infection of primary b...

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Detalles Bibliográficos
Autores principales: Wark, Peter A.B., Johnston, Sebastian L., Bucchieri, Fabio, Powell, Robert, Puddicombe, Sarah, Laza-Stanca, Vasile, Holgate, Stephen T., Davies, Donna E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213100/
https://www.ncbi.nlm.nih.gov/pubmed/15781584
http://dx.doi.org/10.1084/jem.20041901

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