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The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein–induced bone formation
Osteoporosis is a major health problem; however, the mechanisms regulating adult bone mass are poorly understood. Cas-interacting zinc finger protein (CIZ) is a nucleocytoplasmic shuttling protein that localizes at cell adhesion plaques that form where osteoblasts attach to substrate. To investigate...
Autores principales: | Morinobu, Mikihiko, Nakamoto, Tetsuya, Hino, Kazunori, Tsuji, Kunikazu, Shen, Zhong-Jian, Nakashima, Kazuhisa, Nifuji, Akira, Yamamoto, Haruyasu, Hirai, Hisamaru, Noda, Masaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213105/ https://www.ncbi.nlm.nih.gov/pubmed/15781586 http://dx.doi.org/10.1084/jem.20041097 |
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