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A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
A combination of genetic and environmental factors can cause autoimmune disease in animals. SKG mice, which are genetically prone to develop autoimmune arthritis, fail to develop the disease under a microbially clean condition, despite active thymic production of arthritogenic autoimmune T cells and...
Autores principales: | Yoshitomi, Hiroyuki, Sakaguchi, Noriko, Kobayashi, Katsuya, Brown, Gordon D., Tagami, Tomoyuki, Sakihama, Toshiko, Hirota, Keiji, Tanaka, Satoshi, Nomura, Takashi, Miki, Ichiro, Gordon, Siamon, Akira, Shizuo, Nakamura, Takashi, Sakaguchi, Shimon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213107/ https://www.ncbi.nlm.nih.gov/pubmed/15781585 http://dx.doi.org/10.1084/jem.20041758 |
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