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TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells
Transforming growth factor (TGF)-β1 is a major pluripotential cytokine with a pronounced immunosuppressive effect and its deficiency results in lethal autoimmunity in mice. However, mechanisms of its immunosuppressive action are not completely understood. Here, we report that TGF-β1 supports the mai...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213134/ https://www.ncbi.nlm.nih.gov/pubmed/15809351 http://dx.doi.org/10.1084/jem.20042276 |