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IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
Cytokine receptor signals have been suggested to stimulate cell differentiation during hemato/lymphopoiesis. Such action, however, has not been clearly demonstrated. Here, we show that adult B cell development in IL-7 (−/−) and IL-7Rα(2/−) mice is arrested at the pre–pro-B cell stage due to insuffic...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213146/ https://www.ncbi.nlm.nih.gov/pubmed/15837809 http://dx.doi.org/10.1084/jem.20050158 |