Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ

Hypertension affects nearly 20% of the population in Western countries and strongly increases the risk for cardiovascular diseases. In the pathogenesis of hypertension, the vasoactive peptide of the renin-angiotensin system, angiotensin II and its G protein–coupled receptors (GPCRs), play a crucial...

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Detalles Bibliográficos
Autores principales: Vecchione, Carmine, Patrucco, Enrico, Marino, Gennaro, Barberis, Laura, Poulet, Roberta, Aretini, Alessandra, Maffei, Angelo, Gentile, Maria Teresa, Storto, Marianna, Azzolino, Ornella, Brancaccio, Mara, Colussi, Gian Luca, Bettarini, Umberto, Altruda, Fiorella, Silengo, Lorenzo, Tarone, Guido, Wymann, Mathias P., Hirsch, Emilio, Lembo, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213159/
https://www.ncbi.nlm.nih.gov/pubmed/15824082
http://dx.doi.org/10.1084/jem.20040995

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