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Vα14 NK T cell–triggered IFN-γ production by Gr-1(+)CD11b(+) cells mediates early graft loss of syngeneic transplanted islets
Pancreatic islet transplantation is a highly promising approach for the treatment of insulin-dependent diabetes mellitus. However, the procedure remains experimental for several reasons, including its low efficiency caused by the early graft loss of transplanted islets. We demonstrate that Gr-1(+)CD...
Autores principales: | Yasunami, Yohichi, Kojo, Satoshi, Kitamura, Hiroshi, Toyofuku, Atsushi, Satoh, Masayuki, Nakano, Masahiko, Nabeyama, Kentaroh, Nakamura, Yoshiichiroh, Matsuoka, Nobuhide, Ikeda, Seiyo, Tanaka, Masao, Ono, Junko, Nagata, Naoki, Ohara, Osamu, Taniguchi, Masaru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213168/ https://www.ncbi.nlm.nih.gov/pubmed/16186183 http://dx.doi.org/10.1084/jem.20050448 |
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