Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

NFATc1 and NFATc2 are functionally redundant in the immune system, but it was suggested that NFATc1 is required exclusively for differentiation of osteoclasts in the skeletal system. Here we provide genetic evidence that NFATc1 is essential for osteoclast differentiation in vivo by adoptive transfer...

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Detalles Bibliográficos
Autores principales: Asagiri, Masataka, Sato, Kojiro, Usami, Takako, Ochi, Sae, Nishina, Hiroshi, Yoshida, Hiroki, Morita, Ikuo, Wagner, Erwin F., Mak, Tak W., Serfling, Edgar, Takayanagi, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213228/
https://www.ncbi.nlm.nih.gov/pubmed/16275763
http://dx.doi.org/10.1084/jem.20051150

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