Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells

The regulation of acetylation is central for the epigenetic control of lineage-specific gene expression and determines cell fate decisions. We provide evidence that the inhibition of histone deacetylases (HDACs) blocks the endothelial differentiation of adult progenitor cells. To define the mechanis...

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Detalles Bibliográficos
Autores principales: Rössig, Lothar, Urbich, Carmen, Brühl, Thomas, Dernbach, Elisabeth, Heeschen, Christopher, Chavakis, Emmanouil, Sasaki, Ken-ichiro, Aicher, Diana, Diehl, Florian, Seeger, Florian, Potente, Michael, Aicher, Alexandra, Zanetta, Lucia, Dejana, Elisabetta, Zeiher, Andreas M., Dimmeler, Stefanie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213253/
https://www.ncbi.nlm.nih.gov/pubmed/15928198
http://dx.doi.org/10.1084/jem.20042097

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