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Divergent and convergent evolution after a common-source outbreak of hepatitis C virus

The genomic sequences of viruses that are highly mutable and cause chronic infection tend to diverge over time. We report that these changes represent both immune-driven selection and, in the absence of immune pressure, reversion toward an ancestral consensus. Sequence changes in hepatitis C virus (...

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Detalles Bibliográficos
Autores principales:	Ray, Stuart C., Fanning, Liam, Wang, Xiao-Hong, Netski, Dale M., Kenny-Walsh, Elizabeth, Thomas, David L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213258/ https://www.ncbi.nlm.nih.gov/pubmed/15939791 http://dx.doi.org/10.1084/jem.20050122

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