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Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion

We tracked pathogenic myelin basic protein-specific CD4(+) effector T cells in early central nervous system (CNS) lesions of experimental autoimmune encephalomyelitis (EAE) by combining two-photon imaging and fluorescence video microscopy. We made two key observations: (a) the majority of the cells...

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Detalles Bibliográficos
Autores principales:	Kawakami, Naoto, Nägerl, U. Valentin, Odoardi, Francesca, Bonhoeffer, Tobias, Wekerle, Hartmut, Flügel, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213265/ https://www.ncbi.nlm.nih.gov/pubmed/15939794 http://dx.doi.org/10.1084/jem.20050011

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