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Bruton's Tyrosine Kinase Is Essential for Human B Cell Tolerance
Most polyreactive and antinuclear antibodies are removed from the human antibody repertoire during B cell development. To elucidate how B cell receptor (BCR) signaling may regulate human B cell tolerance, we tested the specificity of recombinant antibodies from single peripheral B cells isolated fro...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213290/ https://www.ncbi.nlm.nih.gov/pubmed/15466623 http://dx.doi.org/10.1084/jem.20040920 |