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The BCR-ABL1 Kinase Bypasses Selection for the Expression of a Pre–B Cell Receptor in Pre–B Acute Lymphoblastic Leukemia Cells

The BCR-ABL1 kinase expressed in acute lymphoblastic leukemia (ALL) drives malignant transformation of human pre–B cells. Comparing genome-wide gene expression profiles of BCR-ABL1 (+) pre–B ALL and normal bone marrow pre–B cells by serial analysis of gene expression, many genes involved in pre–B ce...

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Detalles Bibliográficos
Autores principales: Klein, Florian, Feldhahn, Niklas, Harder, Lana, Wang, Hui, Wartenberg, Maria, Hofmann, Wolf-Karsten, Wernet, Peter, Siebert, Reiner, Müschen, Markus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213306/
https://www.ncbi.nlm.nih.gov/pubmed/14993251
http://dx.doi.org/10.1084/jem.20031637