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Activation and Tolerance in CD4(+) T Cells Reactive to an Immunoglobulin Variable Region
Antibody diversity creates an immunoregulatory challenge for T cells that must cooperate with B cells, yet discriminate between self and nonself. To examine the consequences of T cell reactions to the B cell receptor (BCR), we generated a transgenic (Tg) line of mice expressing a T cell receptor (TC...
Autores principales: | Snyder, Christopher M., Aviszus, Katja, Heiser, Ryan A., Tonkin, Daniel R., Guth, Amanda M., Wysocki, Lawrence J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213315/ https://www.ncbi.nlm.nih.gov/pubmed/15226360 http://dx.doi.org/10.1084/jem.20031234 |
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