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Class Switching in B Cells Lacking 3′ Immunoglobulin Heavy Chain Enhancers
The 40-kb region downstream of the most 3′ immunoglobulin (Ig) heavy chain constant region gene (Cα) contains a series of transcriptional enhancers speculated to play a role in Ig heavy chain class switch recombination (CSR). To elucidate the function of this putative CSR regulatory region, we gener...
Autores principales: | Manis, John P., van der Stoep, Nienke, Tian, Ming, Ferrini, Roger, Davidson, Laurie, Bottaro, Andrea, Alt, Frederick W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213411/ https://www.ncbi.nlm.nih.gov/pubmed/9782119 |
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