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Primary Role for GI Protein Signaling in the Regulation of Interleukin 12 Production and the Induction of T Helper Cell Type 1 Responses

We explored the role of Gi protein signaling in the regulation of interleukin (IL)-12 production and T helper cell type 1 (Th1) T cell differentiation. In initial studies, we showed that treatment of normal mice with pertussis toxin (PT), which inhibits Gi protein signaling, enhanced the capacity of...

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Detalles Bibliográficos
Autores principales:	He, Jianping, Gurunathan, Sanjay, Iwasaki, Akiko, Ash-Shaheed, Belinda, Kelsall, Brian L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213427/ https://www.ncbi.nlm.nih.gov/pubmed/10790434

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