Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways

Heat shock proteins (HSPs) derived from tumors or virally infected cells can stimulate antigen-specific CD8(+) T cell responses in vitro and in vivo. Although this antigenicity is known to arise from HSP-associated peptides presented to the immune system by major histocompatibility complex (MHC) cla...

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Detalles Bibliográficos
Autores principales: Castellino, Flora, Boucher, Philip E., Eichelberg, Katrin, Mayhew, Mark, Rothman, James E., Houghton, Alan N., Germain, Ronald N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213527/
https://www.ncbi.nlm.nih.gov/pubmed/10839810

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