Cargando…

Effects of in Vivo Cd8(+) T Cell Depletion on Virus Replication in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

The role of CD8(+) T lymphocytes in controlling replication of live, attenuated simian immunodeficiency virus (SIV) was investigated as part of a vaccine study to examine the correlates of protection in the SIV/rhesus macaque model. Rhesus macaques immunized for >2 yr with nef-deleted SIV (SIVmac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Metzner, Karin J., Jin, Xia, Lee, Fred V., Gettie, Agegnehu, Bauer, Daniel E., Di Mascio, Michele, Perelson, Alan S., Marx, Preston A., Ho, David D., Kostrikis, Leondios G., Connor, Ruth I.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213531/ https://www.ncbi.nlm.nih.gov/pubmed/10839807

Ejemplares similares

Dramatic Rise in Plasma Viremia after CD8(+) T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques
por: Jin, Xia, et al.
Publicado: (1999)

Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques
por: Aravantinou, Meropi, et al.
Publicado: (2017)

Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques
por: Metzner, Karin J, et al.
Publicado: (2006)

Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques
por: Bauer, Anya, et al.
Publicado: (2023)

Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques
por: Winkler, Michael, et al.
Publicado: (2019)

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance
por: Vinton, Carol L., et al.
Publicado: (2019)

Early Regeneration of Thymic Progenitors in Rhesus Macaques Infected with Simian Immunodeficiency Virus
por: Wykrzykowska, Joanna J., et al.
Publicado: (1998)

Transmitted/Founder Simian Immunodeficiency Virus Envelope Sequences in Vesicular Stomatitis and Semliki Forest Virus Vector Immunized Rhesus Macaques
por: Gambhira, Ratish, et al.
Publicado: (2014)

Electrostatic Potential of Human Immunodeficiency Virus Type 2 and Rhesus Macaque Simian Immunodeficiency Virus Capsid Proteins
por: Bozek, Katarzyna, et al.
Publicado: (2012)

CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques
por: Mavigner, Maud, et al.
Publicado: (2021)

Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques
por: Pahar, Bapi, et al.
Publicado: (2022)

Quantification of Viral RNA and DNA Positive Cells in Tissues From Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus Infected Controller and Progressor Rhesus Macaques
por: Pahar, Bapi, et al.
Publicado: (2019)

Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques
por: Haeseleer, Françoise, et al.
Publicado: (2021)

Downregulation of CCR5 on brain perivascular macrophages in simian immunodeficiency virus‐infected rhesus macaques
por: Hattler, Julian B., et al.
Publicado: (2023)

Simian immunodeficiency virus-infected rhesus macaques with AIDS co-develop cardiovascular pathology and encephalitis
por: White, Kevin S., et al.
Publicado: (2023)

Induction of B Cell Hyperplasia in Simian Immunodeficiency Virus–Infected Rhesus Macaques with the Simian Homologue of Kaposi's Sarcoma–Associated Herpesvirus
por: Wong, Scott W., et al.
Publicado: (1999)

Immunogenicity of DNA Vaccines Encoding Simian Immunodeficiency Virus Antigen Targeted to Dendritic Cells in Rhesus Macaques
por: Tenbusch, Matthias, et al.
Publicado: (2012)

Early Detection of Simian Immunodeficiency Virus in the Central Nervous System Following Oral Administration to Rhesus Macaques
por: Milush, Jeffrey M., et al.
Publicado: (2013)

Enhanced Intestinal TGF-β/SMAD-Dependent Signaling in Simian Immunodeficiency Virus Infected Rhesus Macaques
por: Boby, Nongthombam, et al.
Publicado: (2021)

Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques
por: Pahar, Bapi, et al.
Publicado: (2012)

Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques
por: Ziani, Widade, et al.
Publicado: (2021)

Use of a Small Molecule CCR5 Inhibitor in Macaques to Treat Simian Immunodeficiency Virus Infection or Prevent Simian–Human Immunodeficiency Virus Infection
por: Veazey, Ronald S., et al.
Publicado: (2003)

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques
Publicado: (1996)

Genetic Imprint of Vaccination on Simian/Human Immunodeficiency Virus Type 1 Transmitted Viral Genomes in Rhesus Macaques
por: Varela, Mariana, et al.
Publicado: (2013)

Rapamycin limits CD4(+) T cell proliferation in simian immunodeficiency virus–infected rhesus macaques on antiretroviral therapy
por: Varco-Merth, Benjamin D., et al.
Publicado: (2022)

Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques
por: Gama, Lucio, et al.
Publicado: (2017)

Modeling the Effects of Morphine on Simian Immunodeficiency Virus Dynamics
por: Vaidya, Naveen K., et al.
Publicado: (2016)

Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques
por: Pahar, Bapi, et al.
Publicado: (2016)

Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections
por: Krebs, Kendall C., et al.
Publicado: (2016)

Effects of an ActRIIB.Fc Ligand Trap on Cardiac Function in Simian Immunodeficiency Virus-Infected Male Rhesus Macaques
por: Guo, Wen, et al.
Publicado: (2018)

Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques
por: Hsu, Denise C., et al.
Publicado: (2018)

Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of Simian Immunodeficiency Virus-Infected Rhesus Macaques
por: Cogswell, Andrew, et al.
Publicado: (2020)

Identification, Characterization, and Transcriptional Reprogramming of Epithelial Stem Cells and Intestinal Enteroids in Simian Immunodeficiency Virus Infected Rhesus Macaques
por: Boby, Nongthombam, et al.
Publicado: (2021)

Longitudinal trajectories of brain volume in combined antiretroviral therapy treated and untreated simian immunodeficiency virus-infected rhesus macaques
por: Liu, Dan, et al.
Publicado: (2021)

Induction of neutralizing antibodies against tier 2 human immunodeficiency virus 1 in rhesus macaques infected with tier 1B simian/human immunodeficiency virus
por: Himeno, Ai, et al.
Publicado: (2019)

T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian- human immunodeficiency virus
Publicado: (1995)

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques
por: Martins, Mauricio A., et al.
Publicado: (2017)

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques
por: Avalos, Claudia R., et al.
Publicado: (2016)

Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques
por: Karsten, Christina B., et al.
Publicado: (2015)

Myoblast mitochondrial respiration is decreased in chronic binge alcohol administered simian immunodeficiency virus‐infected antiretroviral‐treated rhesus macaques
por: Duplanty, Anthony A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2u739k7rvmmb4sm0cuu9cmjb7a