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Modular Design of Cys-loop Ligand-gated Ion Channels: Functional 5-HT(3) and GABA ρ1 Receptors Lacking the Large Cytoplasmic M3M4 Loop
Cys-loop receptor neurotransmitter-gated ion channels are pentameric assemblies of subunits that contain three domains: extracellular, transmembrane, and intracellular. The extracellular domain forms the agonist binding site. The transmembrane domain forms the ion channel. The cytoplasmic domain is...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213565/ https://www.ncbi.nlm.nih.gov/pubmed/18227272 http://dx.doi.org/10.1085/jgp.200709896 |