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Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

Prohibitin 1 (PHB1) is a highly conserved protein that is mainly localized to the inner mitochondrial membrane and has been implicated in regulating mitochondrial function in yeast. Because mitochondria are emerging as an important regulator of vascular homeostasis, we examined PHB1 function in endo...

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Detalles Bibliográficos
Autores principales: Schleicher, Michael, Shepherd, Benjamin R., Suarez, Yajaira, Fernandez-Hernando, Carlos, Yu, Jun, Pan, Yong, Acevedo, Lisette M., Shadel, Gerald S., Sessa, William C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213620/
https://www.ncbi.nlm.nih.gov/pubmed/18195103
http://dx.doi.org/10.1083/jcb.200706072