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Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence
Prohibitin 1 (PHB1) is a highly conserved protein that is mainly localized to the inner mitochondrial membrane and has been implicated in regulating mitochondrial function in yeast. Because mitochondria are emerging as an important regulator of vascular homeostasis, we examined PHB1 function in endo...
Autores principales: | Schleicher, Michael, Shepherd, Benjamin R., Suarez, Yajaira, Fernandez-Hernando, Carlos, Yu, Jun, Pan, Yong, Acevedo, Lisette M., Shadel, Gerald S., Sessa, William C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213620/ https://www.ncbi.nlm.nih.gov/pubmed/18195103 http://dx.doi.org/10.1083/jcb.200706072 |
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