Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

Calorie restriction (CR), the only non-genetic intervention known to slow aging and extend life span in organisms ranging from yeast to mice, has been linked to the down-regulation of Tor, Akt, and Ras signaling. In this study, we demonstrate that the serine/threonine kinase Rim15 is required for ye...

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Detalles Bibliográficos
Autores principales: Wei, Min, Fabrizio, Paola, Hu, Jia, Ge, Huanying, Cheng, Chao, Li, Lei, Longo, Valter D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213705/
https://www.ncbi.nlm.nih.gov/pubmed/18225956
http://dx.doi.org/10.1371/journal.pgen.0040013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213705/
https://www.ncbi.nlm.nih.gov/pubmed/18225956
http://dx.doi.org/10.1371/journal.pgen.0040013

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