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THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS
The electrophoretic mobility of human red cell ghosts decreases in the presence of chicken serum. The decrease is not directly due to the presence of adsorbed material but to a change which is catalyzed by the foreign substance. It is suggested that abnormal serum materials resulting from disease ma...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1938
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213734/ https://www.ncbi.nlm.nih.gov/pubmed/19873087 |
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author | Byler, W. H. Rozendaal, H. M. |
author_facet | Byler, W. H. Rozendaal, H. M. |
author_sort | Byler, W. H. |
collection | PubMed |
description | The electrophoretic mobility of human red cell ghosts decreases in the presence of chicken serum. The decrease is not directly due to the presence of adsorbed material but to a change which is catalyzed by the foreign substance. It is suggested that abnormal serum materials resulting from disease may serve as catalysts. Fragments of broken cells have the same mobility as whole cells at first, then decrease even in pure salt suspension, while the whole cells remain essentially unchanged for hours. The results suggest that the slow change of whole cells, the change of ghosts in the presence of foreign serum, and the change of fragments are all manifestations of the same modification of structure or composition of the cell surface. |
format | Text |
id | pubmed-2213734 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1938 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22137342008-04-23 THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS Byler, W. H. Rozendaal, H. M. J Gen Physiol Article The electrophoretic mobility of human red cell ghosts decreases in the presence of chicken serum. The decrease is not directly due to the presence of adsorbed material but to a change which is catalyzed by the foreign substance. It is suggested that abnormal serum materials resulting from disease may serve as catalysts. Fragments of broken cells have the same mobility as whole cells at first, then decrease even in pure salt suspension, while the whole cells remain essentially unchanged for hours. The results suggest that the slow change of whole cells, the change of ghosts in the presence of foreign serum, and the change of fragments are all manifestations of the same modification of structure or composition of the cell surface. The Rockefeller University Press 1938-09-20 /pmc/articles/PMC2213734/ /pubmed/19873087 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Byler, W. H. Rozendaal, H. M. THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title | THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title_full | THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title_fullStr | THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title_full_unstemmed | THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title_short | THE ELECTROPHORETIC MOBILITY OF HUMAN ERYTHROCYTES—WHOLE CELLS, GHOSTS, AND FRAGMENTS |
title_sort | electrophoretic mobility of human erythrocytes—whole cells, ghosts, and fragments |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213734/ https://www.ncbi.nlm.nih.gov/pubmed/19873087 |
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