PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE

1. The ability of crystalline ribonuclease to hydrolyze proteins is due to impurities present in the preparations and not to an intrinsic property of the ribonuclease molecule. The amounts of these impurities vary enormously with different preparations. 2. The dangers inherent in the use of crystall...

Descripción completa

Detalles Bibliográficos
Autor principal: McDonald, Margaret R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213741/
https://www.ncbi.nlm.nih.gov/pubmed/18885674
_version_ 1782148942940602368
author McDonald, Margaret R.
author_facet McDonald, Margaret R.
author_sort McDonald, Margaret R.
collection PubMed
description 1. The ability of crystalline ribonuclease to hydrolyze proteins is due to impurities present in the preparations and not to an intrinsic property of the ribonuclease molecule. The amounts of these impurities vary enormously with different preparations. 2. The dangers inherent in the use of crystalline enzymes as specific tools, without assaying them for all possible interfering impurities, are emphasized.
format Text
id pubmed-2213741
institution National Center for Biotechnology Information
language English
publishDate 1948
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22137412008-04-23 PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE McDonald, Margaret R. J Gen Physiol Article 1. The ability of crystalline ribonuclease to hydrolyze proteins is due to impurities present in the preparations and not to an intrinsic property of the ribonuclease molecule. The amounts of these impurities vary enormously with different preparations. 2. The dangers inherent in the use of crystalline enzymes as specific tools, without assaying them for all possible interfering impurities, are emphasized. The Rockefeller University Press 1948-09-20 /pmc/articles/PMC2213741/ /pubmed/18885674 Text en Copyright © Copyright, 1948, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
McDonald, Margaret R.
PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title_full PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title_fullStr PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title_full_unstemmed PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title_short PROTEOLYTIC CONTAMINANTS OF CRYSTALLINE RIBONUCLEASE
title_sort proteolytic contaminants of crystalline ribonuclease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213741/
https://www.ncbi.nlm.nih.gov/pubmed/18885674
work_keys_str_mv AT mcdonaldmargaretr proteolyticcontaminantsofcrystallineribonuclease

Ejemplares similares