ISOLATION OF CRYSTALLINE RICIN

A toxic crystalline protein has been isolated from crude extracts of castor bean meal. Ultracentrifuge and electrophoresis tests show the crystalline protein to become fairly homogeneous after three or four crystallizations. This is also confirmed by toxicity measurements. Solubility tests, however,...

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Detalles Bibliográficos
Autores principales: Kunitz, M., McDonald, Margaret R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213745/
https://www.ncbi.nlm.nih.gov/pubmed/18885673
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author Kunitz, M.
McDonald, Margaret R.
author_facet Kunitz, M.
McDonald, Margaret R.
author_sort Kunitz, M.
collection PubMed
description A toxic crystalline protein has been isolated from crude extracts of castor bean meal. Ultracentrifuge and electrophoresis tests show the crystalline protein to become fairly homogeneous after three or four crystallizations. This is also confirmed by toxicity measurements. Solubility tests, however, indicate the presence of more than one protein component in the crystalline material, possibly in the form of a solid solution which cannot be separated into its components by repeated crystallization under the present technique.
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spelling pubmed-22137452008-04-23 ISOLATION OF CRYSTALLINE RICIN Kunitz, M. McDonald, Margaret R. J Gen Physiol Article A toxic crystalline protein has been isolated from crude extracts of castor bean meal. Ultracentrifuge and electrophoresis tests show the crystalline protein to become fairly homogeneous after three or four crystallizations. This is also confirmed by toxicity measurements. Solubility tests, however, indicate the presence of more than one protein component in the crystalline material, possibly in the form of a solid solution which cannot be separated into its components by repeated crystallization under the present technique. The Rockefeller University Press 1948-09-20 /pmc/articles/PMC2213745/ /pubmed/18885673 Text en Copyright © Copyright, 1948, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Kunitz, M.
McDonald, Margaret R.
ISOLATION OF CRYSTALLINE RICIN
title ISOLATION OF CRYSTALLINE RICIN
title_full ISOLATION OF CRYSTALLINE RICIN
title_fullStr ISOLATION OF CRYSTALLINE RICIN
title_full_unstemmed ISOLATION OF CRYSTALLINE RICIN
title_short ISOLATION OF CRYSTALLINE RICIN
title_sort isolation of crystalline ricin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213745/
https://www.ncbi.nlm.nih.gov/pubmed/18885673
work_keys_str_mv AT kunitzm isolationofcrystallinericin
AT mcdonaldmargaretr isolationofcrystallinericin

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