Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry

The cardiac glycoside ouabain inhibits transepithelial sodium transport in the toad urinary bladder. It is shown that this drug reduces the rate coefficient for sodium exit at the serosal pump site. In addition, ouabain inhibits entry across the mucosal border whenever the electrochemical potential...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214927/
https://www.ncbi.nlm.nih.gov/pubmed/807674
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description The cardiac glycoside ouabain inhibits transepithelial sodium transport in the toad urinary bladder. It is shown that this drug reduces the rate coefficient for sodium exit at the serosal pump site. In addition, ouabain inhibits entry across the mucosal border whenever the electrochemical potential gradient for sodium is made less favorable. The data are interpreted as indicating the existence of two separate pathways for sodium entry, one of which is ouabain inhibitable.
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spelling pubmed-22149272008-04-23 Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry J Gen Physiol Articles The cardiac glycoside ouabain inhibits transepithelial sodium transport in the toad urinary bladder. It is shown that this drug reduces the rate coefficient for sodium exit at the serosal pump site. In addition, ouabain inhibits entry across the mucosal border whenever the electrochemical potential gradient for sodium is made less favorable. The data are interpreted as indicating the existence of two separate pathways for sodium entry, one of which is ouabain inhibitable. The Rockefeller University Press 1975-04-01 /pmc/articles/PMC2214927/ /pubmed/807674 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title_full Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title_fullStr Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title_full_unstemmed Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title_short Action of ouabain on sodium transport in toad urinary bladder, Evidence for two pathways for sodium entry
title_sort action of ouabain on sodium transport in toad urinary bladder, evidence for two pathways for sodium entry
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214927/
https://www.ncbi.nlm.nih.gov/pubmed/807674

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