Dog red blood cells: Na and K diffusion potentials with extracellular ATP

External ATP causes a prompt increase in the Na and K permeability of dog red blood cells. By manipulating intra- and extracellular ion composition it is possible to observe ATP-induced net fluxes which can be explained in terms of the contribution of Na or K diffusion potentials to the membrane pot...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215052/
https://www.ncbi.nlm.nih.gov/pubmed/853285
_version_ 1782148988293611520
collection PubMed
description External ATP causes a prompt increase in the Na and K permeability of dog red blood cells. By manipulating intra- and extracellular ion composition it is possible to observe ATP-induced net fluxes which can be explained in terms of the contribution of Na or K diffusion potentials to the membrane potential. Measurements of membrane voltage by a fluorescent dye technique confirm the existence of such potentials. A rough calculation of chloride permeability gives a value of the order of 10(-8) cm/s, which agrees with results in other species. The cells appear to be somewhat more permeable to bromide than to chloride.
format Text
id pubmed-2215052
institution National Center for Biotechnology Information
language English
publishDate 1977
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22150522008-04-23 Dog red blood cells: Na and K diffusion potentials with extracellular ATP J Gen Physiol Articles External ATP causes a prompt increase in the Na and K permeability of dog red blood cells. By manipulating intra- and extracellular ion composition it is possible to observe ATP-induced net fluxes which can be explained in terms of the contribution of Na or K diffusion potentials to the membrane potential. Measurements of membrane voltage by a fluorescent dye technique confirm the existence of such potentials. A rough calculation of chloride permeability gives a value of the order of 10(-8) cm/s, which agrees with results in other species. The cells appear to be somewhat more permeable to bromide than to chloride. The Rockefeller University Press 1977-04-01 /pmc/articles/PMC2215052/ /pubmed/853285 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title_full Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title_fullStr Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title_full_unstemmed Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title_short Dog red blood cells: Na and K diffusion potentials with extracellular ATP
title_sort dog red blood cells: na and k diffusion potentials with extracellular atp
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215052/
https://www.ncbi.nlm.nih.gov/pubmed/853285

Ejemplares similares