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Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes

We have investigated the steady-state potential and current distributions resulting from current injection into a close-fitting channel into which a squid axon is placed. Hybrid computer solutions of the cable equations, using the Hodgkin-Huxley equations to give the membrane current density, were i...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1979
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215205/
https://www.ncbi.nlm.nih.gov/pubmed/479813
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collection PubMed
description We have investigated the steady-state potential and current distributions resulting from current injection into a close-fitting channel into which a squid axon is placed. Hybrid computer solutions of the cable equations, using the Hodgkin-Huxley equations to give the membrane current density, were in good agreement with experimental observations. A much better fit was obtained when the Hodgkin-Huxley leakage conductance was reduced fivefold.
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spelling pubmed-22152052008-04-23 Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes J Gen Physiol Articles We have investigated the steady-state potential and current distributions resulting from current injection into a close-fitting channel into which a squid axon is placed. Hybrid computer solutions of the cable equations, using the Hodgkin-Huxley equations to give the membrane current density, were in good agreement with experimental observations. A much better fit was obtained when the Hodgkin-Huxley leakage conductance was reduced fivefold. The Rockefeller University Press 1979-06-01 /pmc/articles/PMC2215205/ /pubmed/479813 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title_full Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title_fullStr Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title_full_unstemmed Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title_short Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
title_sort nonlinear cable equations for axons. ii. computations and experiments with external current electrodes
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215205/
https://www.ncbi.nlm.nih.gov/pubmed/479813